Top 10 Most Addictive Painkillers


Addictive Pain Relievers

There are a number of different drugs that can ease chronic and short-term pain. Many of these fall into the opioid category, also known as narcotic pain relievers. These drugs include morphine and codeine, as well as many synthetic modifications of these drugs.

It is important to be cautious when taking pain relief medications. The treatment may be more dangerous than the underlying cause of the pain. You are less likely to become addicted to pain-relieving drugs when taking them as prescribed for their intended purpose. Yet, many of these medications also produce a “high” that can become addicting to some patients.

It is this feeling of euphoria that the National Institute on Drug Abuse (NIDA) says that some people become dependent on. It is most likely to happen when someone takes a higher dose than they were prescribed or if they are improperly prescribed the medication.

Pain medication over-use (sometimes called medication abuse or narcotic abuse) has become one of the most prevalent forms of drug abuse in the United States. One of the reasons is that these medications are sometimes over-prescribed. In some cases, someone may not really need such strong pain relief and, in other cases, it’s prescribed for longer than it’s truly needed.



More potent than morphine, fentanyl (brand names include Actiq, Duragesic, and Sublimaze) is used most often to treat patients with severe or post-surgical pain. It is also used for those who have become physically tolerant of opiates. It’s available as a lozenge, injectable solution, or skin patch

Street names for fentanyl include Apache, China Girl, China White, Dance Fever, Friend, Goodfella, Jackpot, Murder 8, Tango and Cash, and TNT. It has also become common for fentanyl to be used in counterfeit drugs and to be cut into illegal drugs such as heroin and cocaine. This adds to the dangers of these drugs because users are often unaware of the fentanyl


OxyContin is a brand name for oxycodone. It is used as an around-the-clock treatment for patients with moderate to severe pain expected to last for an extended period of time. It’s available as a tablet.

On the street, OxyContin may be called O.C., Oxycet, Oxycotton, Oxy, or Hillbilly Heroin.


Demerol is a brand name for meperidine. This pain medication is often used to help put people to sleep before a surgical procedure. It is also used to treat moderate to severe pain, such as that experienced after childbirth. Demerol is available as an oral solution, injectable solution, and oral tablet.

Street names for Demerol include Demmies and Pain Killer.


Hydrocodone (brand names include Vicodin, Norco, and Zohydro, among others) is used to treat moderate to severe pain resulting from a chronic condition, injury, or surgical procedure. It’s available as an oral syrup and oral tablet.

When sold on the black market, it may be called Vike or Watson-387.


Morphine is a natural opiate that is sold under the brand names Duramorph and MS Contin. It is prescribed to help treat severe ongoing pain such as that related to cancer or cancer treatment. This painkiller is available as an injectable solution, capsule, tablet, and suppository.

You may hear morphine simply called M on the street, though it’s also known as Miss Emma, Monkey, and White Stuff.


Percocet is similar to OxyContin. It contains a combination of acetaminophen and oxycodone and is available as a capsule, tablet, and oral solution.

On the street, it may also be called Hillbilly Heroin or simply as Percs.


Codeine is a natural opiate that is a commonly prescribed pain reliever. The effects only last for a few hours, so it is often prescribed along with acetaminophen or aspirin. Codeine is available as a tablet, capsule, or liquid.

Many brand names are sold and codeine has many street names, including Captain Cody, Cody, Lean, Schoolboy, Sizzurp, and Purple Drank.


Methadone is most often associated with people who are trying to safely quit a heroin addiction. It is, however, used as an opiate pain reliever and it can be misused as well. Brand names include Dolophine and Methadose and it comes in tablet and liquid forms.

Street names include Amidone and Fizzies. When it is used with MDMA, it is known as Chocolate Chip Cookies.


Dilaudid is a brand name for hydromorphone. It is mostly used in a hospital setting and administered through an IV following surgery. Dilaudid is intended for short-term pain relief and is also available as an oral solution, tablet, and suppository.

In illicit uses, Dilaudid may simply be called D or known by the names Dillies, Footballs, Juice, and Smack.


Oxymorphone is sold under the brand names Opana, Numorphan, and Numorphone. It is prescribed to treat moderate to severe pain and is available in both immediate- and extended-release tablets.

This opiate is blue and has an octagon shape, so it’s street names reflect this: Biscuits, Blue Heaven, Blues, Mrs. O, O Bomb, Octagons, and Stop Signs.

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